Gray matter is located on the surface of the cerebral cortex and also includes deep brain structures such as the thalamus and basal ganglia. White matter is located beneath the gray matter of the cerebral cortex and comprises long neural pathways which are responsible for transferring information between gray matter regions where the processing of information occurs.
Shawn Christ and his team are using magnetic resonance imaging to learn more about the effects of PKU on the brain and to assist scientists in developing therapeutic drugs that help treat and control the disease.